NanoInnovation 2025 will be held from September 15 to 19, 2025, in the historic San Gallo cloister, at the Faculty of Civil and Industrial Engineering of the Sapienza University of Rome (Via Eudossiana 18). The event represents a well-established national meeting point for the wide and multidisciplinary community involved in the development of nanotechnology and its integration with other key enabling technologies (KETs), in all fields of application. This year, topics underlying Innovation, Nanomedicine, Nanomaterials, Energy, and related ecosystems will receive special attention, with the aim of enhancing the technological and social return on investment in research and higher education.   NanoInnovation 2025 will once more gather researchers, technologists, managers, entrepreneurs, and investors who will share their experiences, opinions, and expectations on the topics proposed this year, with constant focus on the world of nanotechnology. Special attention will be paid to the direct involvement of young researchers, doctoral students, and students, to support their inclusion in the professional world and foster their role as protagonists in the future of our Society.